Detailed Analysis of NFL Week 6 2025
Week 6 of the 2025 NFL season presents exciting and promising matchups. Here, at Alofoke Deportes, we provide you with everything you need to know to stay on top of the action. Following his impressive 206-yard rushing performance last week, Panthers running back Rico Dowdle will look to repeat his success against the Cowboys, his former team. The Buccaneers will host the 49ers in a matchup between teams with a 4-1 record. In addition, the Lions will visit the Chiefs’ Arrowhead Stadium for the second time in three seasons. Our NFL Nation reporters will take you into the locker room with the highlights of the week. In addition, we will offer you key statistics and betting predictions for each game. Seth Walder, statistics analyst, will share his bold predictions, while Eric Moody, fantasy analyst, will give you valuable information. We also include the quality ratings of the Football Power Index (FPI) matchups and game projections. Pamela Maldonado, Moody and Walder offer us their final score predictions for each game. The week culminates with a “Monday Night Football” double-header between the Bills and the Falcons, and the Bears against the Commanders. (Game times are on Sunday, unless otherwise noted).Featured Matches of Week 6
- Jets vs. Broncos
- Rams vs. Ravens
- Seahawks vs. Jaguars
- Cardinals vs. Colts
- Chargers vs. Dolphins
Analysis of the Matches
Jets (0-5) vs. Broncos (3-2)9:30 a.m. ET | NFL Network | Matchup Rating: 44.9/100
ESPN BET: DEN -6.5 (43.5 O/U)What we’re hearing about the Jets: Defensive tackle Quinnen Williams summed up the situation: “We’re 0-5 and the defense has been the problem, the reason we’re 0-5.” The Jets haven’t managed any fumble recoveries and have only managed three sacks in the last four games. Pressure on the passer was a focus in practice this week, but standing out against the Broncos won’t be easy, as they’ve allowed only five sacks this season. – Rich CiminiWhat we heard about the Broncos: The Broncos departed for London a few hours after their victory over the Eagles, the most significant triumph of Sean Payton’s tenure in Denver. Payton stated that he would not allow the game against the Jets at Tottenham Stadium to become a trap for the Broncos, who have a 3-2 record. “Every week is the ability to refocus on the next challenge,” Payton said. “… These guys understand that in our league, it’s different from college football. We don’t have the opportunity to play against a Division I-AA or FCS school. These are all professional teams, and we will treat them that way.” – Jeff LegwoldKey statistic: Broncos quarterback Bo Nix only managed 60 passing yards in the 10-9 victory over the Jets last season, the only time in his career he has been limited to under 130 passing yards. – Alofoke Deportes ResearchBold Prediction: Jets running back Breece Hall will be limited to one or no receptions. The Jets throw to their running back 26% of the time, the fourth-highest rate of any team. However, the Broncos’ defense, which focuses on man coverage, allows a lower target rate to running backs (12%) than any other team. – WalderInjuries: Jets | BroncosFantasy Information: Jets quarterback Justin Fields scored 25.9 fantasy points in Week 5. However, he faces a Broncos defense that has allowed the fewest fantasy points and yards per carry to quarterbacks this season. Fantasy managers should consider switching to a replacement player this week. – MoodyRecommended bet: Teams favored by at least four points in international matches have a 16-9 ATS record and 19-6 in direct wins. – Alofoke Deportes ResearchPredictions:
Maldonado: Broncos 31, Jets 6
Moody: Broncos 30, Jets 17
Walder: Broncos 22, Jets 12
FPI Prediction: DEN, 70.8% (by an average of 8.3 points)Must-reads from the matchup: The Jets vow to keep fighting despite being the NFL’s only winless team … How the Broncos, Elway built an NFL general manager tree.Rams (3-2) vs. Ravens (1-4)
1 p.m. ET | Fox | Matchup Rating: 74.3/100
ESPN BET: LAR -7.5 (44.5 O/U)What we’re hearing about the Rams: After five weeks, Rams quarterback Matthew Stafford leads the league with 1,503 passing yards and is just 50 yards away from surpassing Dan Marino (61,361) to become the ninth player with the most passing yards in NFL history. The Ravens have allowed 177 points this season, the most in a five-game span in franchise history, according to research by Alofoke Deportes. Baltimore is also allowing an average of 262.6 passing yards per game, the second-worst mark in the NFL. – Sarah Barshop
What we’re hearing about the Ravens: Running back Derrick Henry has been limited to 50 rushing yards or less in four straight games, which matches the worst streak of his career. It’s important for Henry to get back on track for the Ravens, who are 10-1 when Henry produces more than 90 rushing yards. However, the Rams, who have the 10th-best run defense in the NFL, have only allowed one running back to gain more than 90 rushing yards this season (Tony Pollard). “We have the best running back in the game,” Ravens center Tyler Linderbaum said, “so we have to find a way to get better.” – Jamison Hensley
Key statistic: The Ravens were outscored by more than 17 points in each of their last two games. They have never lost three consecutive games by at least three scores in franchise history. – Alofoke Deportes ResearchBold Prediction: The Rams will complete multiple passes of over 40 yards. After five weeks, the Rams have the most air yards per attempt in the league with 8.5, and the Baltimore defense is allowing 8.0 air yards per target (the fourth most). Although I believe the Ravens defense will eventually figure it out, the best bet for now is that they will continue to struggle in the short term. – WalderInjuries: Rams | Ravens
Maldonado: Rams 23, Ravens 20
Moody: Rams 31, Ravens 16
Walder: Rams 30, Ravens 14
FPI Prediction: LAR, 58.7% (by an average of 3.3 points)Must-reads from the matchup: After several missed field goals, the pressure is on the Rams’ kicking unit … Bateman says the 1-4 Ravens ‘deserve all the criticism’ … The AFC North quarterback landscape isn’t what it was at the start of the season: What’s going on?Seahawks (3-2) vs. Jaguars (4-1)
1 p.m. ET | Fox | Matchup Rating: 57.5/100
ESPN BET: SEA -1.5 (47.5 O/U)What we’re hearing about the Seahawks: The Seahawks’ defense was battered in Week 5, largely due to their inability to pressure the Buccaneers’ quarterback, Baker Mayfield, who was only hit once in 38 pass attempts. Next up is Jacksonville’s Trevor Lawrence, who has only been sacked six times in five games. Coach Mike Macdonald attributed the Jaguars’ ability to stay on schedule and avoid obvious passing situations as a factor, along with Lawrence’s quick decisions. “The receivers are getting open and he’s throwing the ball on time,” Macdonald said. “He’s throwing with accuracy and they’re protecting him.” – Brady HendersonWhat we’re hearing about the Jaguars: The Jaguars’ offensive strength is their running game (fifth in the NFL with 137 rushing yards per game) and they will face their toughest test of the season against Seattle, which has the third-best run defense in the league (83 yards per game). Running back Travis Etienne Jr. described the Seahawks’ defensive line as game wreckers and said they present “a lot of disruption.” The Jaguars are likely to be without center Robert Hainsey (hamstring), so seventh-round rookie Jonah Monheim will step in as a starter, a difficult task for his first start. – Michael DiRoccoKey statistic: The Jaguars have 14 ball recoveries this season, the most in the NFL. – Alofoke Deportes ResearchBold Prediction: The Seahawks release quarterback Sam Darnold and have him throw 40 pass attempts. Yes, even against a Jaguars defense that ranks third in EPA per allowed pass. The Seahawks have been much more efficient passing than running this season (.28 EPA per play vs. minus 0.07) and need to lean more into that part of their game. Also, the Jaguars have a new cornerback in Greg Newsome II, who might still be getting used to the defense. – WalderInjuries: Seahawks | JaguarsFantasy Information: Travis Hunter had a season-high in offensive snaps and also recorded a career-high in receiving yards for the second straight game. The Seahawks’ secondary is a middle-of-the-road unit and just allowed Bucs rookie receiver Emeka Egbuka to score 31.3 fantasy points against them. Hunter could have a standout performance. – MoodyRecommended bet: The Seahawks have won eight consecutive away games. They have a 9-1 record under Macdonald in the last two seasons. – Alofoke Deportes ResearchPrognostications:
Maldonado: Seahawks 17, Jaguars 16
Moody: Jaguars 27, Seahawks 24
Walder: Seahawks 30, Jaguars 24
FPI Prediction: JAX, 50.2% (by an average of 0.1 points)Must-read from the matchup: Seahawks quarterback Darnold showed his potential in the Week 5 loss … Jaguars linebacker Lloyd is flourishing in the new defense … Jaguars get Newsome, send Campbell to the BrownsCardinals (2-3) vs. Colts (4-1)
1 p.m. ET | Fox | Matchup Rating: 58.1/100
ESPN BET: IND -7.5 (46.5 O/U)
What we’re hearing about the Cardinals: Marvin Harrison Jr. has finally found a rhythm in the last two weeks, resulting in a significant increase in explosive plays. In Week 4 and Week 5 combined, both losses, Harrison was responsible for seven explosive plays, compared to just two in the first three games. This week is another opportunity for Harrison to add to his total, as the Colts have conceded 23 explosive passes this season, 12 in the last two games. “I mean, it helps to catch explosives,” Harrison said. “I think in both games, that certainly helps and then you get a rhythm from there.” – Josh Weinfuss
What we’re hearing about the Colts: This will be an interesting matchup because the Colts are second in points per game (32.6) and the Cardinals are allowing only 19.2 points per game. Can the Colts find solutions for a defense that has limited the 49ers and Seahawks in recent weeks? It will be one of the most important tests for quarterback Daniel Jones and the Colts, who have been creating weekly fireworks. In particular, the Cardinals have not allowed a 100-yard rushing performance, while Colts running back Jonathan Taylor averages 96 yards per game. – Stephen HolderKey statistic: Jones leads the NFL in QBR outside the pocket when under pressure and on third down. He is second in total QBR this season (79.6), behind Seahawks quarterback Sam Darnold. – Alofoke Deportes ResearchBold Prediction: The Colts will average less than 4.0 yards per carry. They face a Cardinals defense that has allowed the lowest EPA per designed carry this season, which could put a lot of pressure on the Colts’ run-focused offense. – Walder
Recommended bet: Cardinals quarterback Kyler Murray has a 27-13-1 ATS record as a visitor in his career, including 22-7-1 ATS as a visiting underdog. He has an 18-6-1 ATS record when receiving at least three points on the road. – Research by Alofoke Deportes
Predictions:Maldonado: Colts 26, Cardinals 24
Moody: Colts 28, Cardinals 23
Walder: Cardinals 19, Colts 16
FPI Prediction: IND, 65.3% (by an average of 5.9 points)Must-reads for the matchup: Cardinals’ Harrison reflects on ‘special game’ against his father’s Colts … Colts sign LB Pratt two days after being released by Raiders … Cardinals quarterback Murray doesn’t practice due to foot injury … Colts sign Badgley to replace injured ShraderChargers (3-2) vs. Dolphins (1-4)
1 p.m. ET | CBS | Matchup Rating: 46.7/100
ESPN BET: LAC -3.5 (43.5 O/U)What we’re hearing about the Chargers: Before trading for Ravens defensive end Odafe Oweh, the Chargers only had one player ranked among the top 125 in pressure rate (LB Tuli Tuipulotu, 12th). Oweh, who ranks 33rd in pressures, is set to debut for Los Angeles on Sunday. “He’s a lot like Khalil Mack. Straight-line rusher, but he’s got speed, he’s got depth, he’s got the ability to set the edge,” said coach Jim Harbaugh. “He’s been a very good, productive young player, on the cusp of his career.” – Kris RhimWhat we’re hearing about the Dolphins: Sunday marks the fourth matchup between quarterbacks Justin Herbert and Tua Tagovailoa as NFL starters, with Tagovailoa’s Dolphins leading the series 2-1. The two quarterbacks were selected with consecutive picks in 2020, but Tagovailoa said he doesn’t communicate much with the other quarterbacks in his draft class. “I know everyone wants to make comparisons with all the guys that were in my draft class,” Tagovailoa said, “but all you can do is be happy for the guys, where they’re at in their football life and wish them the best. That’s all I’d like to do and hope for the same in return.” – Marcel Louis-JacquesKey statistic: Since Mike McDaniel took over as Dolphins coach in 2022, they have a 3-14 record against teams that started the game with winning records. – Alofoke Deportes ResearchBold Prediction: Chargers running backs Hassan Haskins and Kimani Vidal will combine for 150 or more rushing yards. The Chargers are generating 3.0 yards before contact per carry, the fifth-best mark in the NFL, while the Dolphins’ defense is allowing 3.2 yards before contact per carry, the second-most in the NFL. – WalderInjuries: Chargers | DolphinsFantasy Information: A reinforced trend in Week 5 is that you’ll want to align running backs against the Dolphins. Carolina’s Rico Dowdle scored 32.4 fantasy points, and with Chargers running back Omarion Hampton landing on injured reserve with an ankle injury, Haskins, who is expected to handle the work on early downs and in the end zone, could be next to benefit. The Dolphins’ defense has allowed the fifth-most fantasy points per game to running backs. – MoodyRecommended bet: Tagovailoa has a 6-3 ATS record and 5-4 in outright wins in his career as a home underdog. – Alofoke Deportes ResearchPrognostications:
Maldonado: Chargers 35, Dolphins 13
Moody: Chargers 26, Dolphins 24
Walder: Chargers 31, Dolphins 13
FPI Prediction: LAC, 60.2% (by an average of 3.9 points)Must-reads from the matchup: Three big questions facing the Chargers after losing two straight games … Dolphins not worried as Tua is limited by hand and hip … McDaniel: Dolphins owner is ‘really frustrated’
